Tamoxifen – British Dragon Pharmaceuticals (INT)

PRODUCT DESCRIPTION

Tamoxifen serves as a treatment for breast cancer in both men and women, particularly in instances where hormone receptors are involved. Its function involves obstructing estrogen’s impact in breast tissue, halting the progression of cancer cells reliant on estrogen for growth.

Apart from breast cancer treatment, Tamoxifen might reduce breast cancer risk in high-risk individuals. It’s occasionally prescribed for ovulation-related infertility issues in women and other medical conditions.

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HOW DOES IT WORK?

Tamoxifen operates as a selective regulator of estrogen receptors, recognized as a SERM. It operates by competitively binding to estrogen receptors in certain tissues, particularly in breast tissue, without activating them fully. This process blocks the effects of estrogen in these tissues by inhibiting its binding, thereby impeding the growth of estrogen-sensitive cancer cells in hormone receptor-positive breast cancer. Essentially, by interfering with estrogen’s action in breast tissue, Tamoxifen helps to prevent the stimulation of cancer cell growth that relies on estrogen.

Dosage 

The recommended quantity of tamoxifen relies on the individual’s particular health status and the intended treatment. Usual amounts for managing breast cancer or other health issues generally range between 20 to 40 milligrams (mg) consumed orally each day, commonly split into one or two doses.

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Benefits

• Treating Hormone Receptor-Positive Breast Cancer: It effectively controls this type of breast cancer by stopping estrogen’s effects on breast tissue, hindering cancer cell growth.
• Breast Cancer Risk Reduction: It might serve as a preventive measure to diminish the chance of developing breast cancer in high-risk individuals.
• Assistance with Fertility: In specific instances, it aids in addressing fertility concerns linked to ovulation issues in women.
• Bone Health: Tamoxifen might help in maintaining or improving bone density in postmenopausal women.

Side effects

• Hot flashes
• Menstrual changes
• Vaginal discharge or dryness
• Mood changes
• Nausea and vomiting
• Fatigue
• Increased risk of blood clots
• Increased risk of uterine cancer

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