Tamoxifen 20

Introduction

Tamoxifen 20 is a high-quality research chemical widely used in scientific and pharmaceutical studies. Known for its role as a selective estrogen receptor modulator (SERM), Tamoxifen 20 has been extensively studied for its applications in breast cancer research, hormonal regulation, and endocrine therapy. With its purity and consistency, it serves as an essential tool for researchers in various fields.

Synonyms

• Tamoxifen Citrate
• Nolvadex
• ICI-46474

CAS Number

CAS No: 10540-29-1

Molecular Formula and Structure

• Molecular Formula: C26H29NO
• Molecular Structure: Tamoxifen is a nonsteroidal compound with a triphenylethylene backbone, which contributes to its unique properties as a SERM.

Purity and Grade

• Purity: ≥ 99% (Pharmaceutical Grade)
• Grade: Laboratory and Research Grade

Physical and Chemical Properties

• Appearance: White to off-white powder
• Molecular Weight: 371.51 g/mol
• Melting Point: 97-98°C
• Solubility:
  • Soluble in ethanol, methanol, and chloroform
  • Slightly soluble in water
• Stability: Stable under standard laboratory conditions

Safety and Handling Information

• Personal Protective Equipment (PPE): Always wear gloves, goggles, and lab coats when handling Tamoxifen 20.
• Avoid inhalation, ingestion, and direct contact with skin or eyes.
• Conduct all experiments in a well-ventilated area or under a fume hood.
• Hazard Classifications:
  • GHS Classification: Harmful if swallowed or inhaled
  • Signal Word: Warning
  • Hazard Statements: H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation)

First-Aid Measures

• Inhalation: Move to fresh air immediately. If breathing is difficult, seek medical attention.
• Skin Contact: Wash thoroughly with soap and water. Remove contaminated clothing.
• Eye Contact: Rinse with plenty of water for at least 15 minutes. Consult a physician if irritation persists.
• Ingestion: Rinse mouth with water. Do not induce vomiting. Seek medical assistance immediately.

Usage and Applications

Tamoxifen 20 is primarily used in:

• Cancer Research:
  • Studying its efficacy in blocking estrogen receptors in breast cancer cells.
  • Investigating its role in reducing the recurrence of estrogen receptor-positive cancers.
• Endocrinology Studies:
  • Researching its effects on hormonal regulation and its anti-estrogenic properties.
• Pharmaceutical Development:
  • Exploring its applications in the treatment of gynecomastia, infertility, and other estrogen-related conditions.
• Tissue-Specific Estrogen Modulation:
  • Studying the selective binding of Tamoxifen to estrogen receptors in different tissues.

Storage Conditions

• Store Tamoxifen 20 in a cool, dry, and well-ventilated area.
• Keep away from excessive heat, moisture, and direct sunlight.
• Ideal storage temperature: 2-8°C (refrigerated).
• Ensure the container is tightly sealed when not in use.

Regulatory Information

• Tamoxifen 20 is intended strictly for laboratory and research purposes.
• Not for human or animal consumption.
• Users must comply with all local and international regulations regarding the purchase, storage, and use of research chemicals.

Frequently Asked Questions (FAQ)

1. What is Tamoxifen 20?

Tamoxifen 20 is a high-purity research chemical used in cancer research, endocrinology studies, and pharmaceutical development as a selective estrogen receptor modulator (SERM).

2. What is the purity level of Tamoxifen 20?

Tamoxifen 20 has a purity level of ≥ 99%, making it suitable for high-precision research purposes.

3. How should Tamoxifen 20 be stored?

Store Tamoxifen 20 in a cool, dry place at a temperature between 2-8°C, away from heat, moisture, and direct sunlight.

4. What are the primary applications of Tamoxifen 20?

Its primary applications include cancer research, hormonal regulation studies, and pharmaceutical development.

5. Is Tamoxifen 20 safe to handle?

Yes, when proper safety precautions are followed. Always wear protective gloves, goggles, and lab coats, and avoid direct contact with the compound.

6. Can Tamoxifen 20 be used for human consumption?

No, Tamoxifen 20 is strictly for research purposes and is not intended for human or animal consumption.