ARIMIROW 1MG/50 TABS (Anastrozole)

Research Chemical Name and Synonyms:

• Name: Anastrozole
• Synonyms:
  • Arimidex
  • 1,3-benzodioxole, 4-(1H-1,2,4-triazol-1-ylmethyl)-, 1-methyl-1H-1,2,4-triazole-3-carbinol
  • 4-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzodioxole

CAS Number:

• CAS Number: 120511-73-1

Molecular Formula and Structure:

• Molecular Formula: C17H19N5
• Molecular Structure: Anastrozole’s structure includes a triazole ring and a benzodioxole component that interacts with aromatase enzymes to inhibit estrogen production.

Purity and Grade:

• Purity: ≥ 99%
• Grade: Pharmaceutical Grade

Physical and Chemical Properties:

• Appearance: White to almost white crystalline powder
• Solubility: Soluble in methanol and ethanol; slightly soluble in water
• Melting Point: 223–226°C
• Stability: Stable under recommended storage conditions
• Odor: Odorless

Safety and Handling Information:

• Precautions: Always wear appropriate personal protective equipment (PPE) when handling the chemical. Avoid inhalation or ingestion.
• Storage: Store in a cool, dry place away from light and moisture. Keep out of reach of children and pets.
• Personal Protective Equipment (PPE): Wear gloves, safety glasses, and lab coats when handling.

First-Aid Measures:

• Inhalation: If inhaled, move the person to fresh air immediately. If symptoms persist, seek medical attention.
• Skin Contact: Wash affected skin with soap and water. Seek medical attention if irritation develops.
• Eye Contact: Rinse eyes with water for at least 15 minutes. If irritation persists, seek medical attention.
• Ingestion: Do not induce vomiting. Rinse mouth thoroughly and seek immediate medical attention.

Usage and Applications:

• Primary Application: Anastrozole is primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It is also sometimes used in combination therapy for fertility treatments.
• Mechanism of Action: By inhibiting the aromatase enzyme, Anastrozole significantly reduces estrogen production, which can slow down the growth of estrogen-dependent cancer cells.
• Dosage: Typically, a 1 mg tablet is taken once daily, with or without food.

Storage Conditions:

• Recommended Storage: Store at room temperature (15–30°C / 59–86°F), away from light and moisture.
• Shelf Life: 2 years from manufacturing date, check packaging for expiration date.

Regulatory Information:

• FDA Approval: Anastrozole is FDA-approved for the treatment of breast cancer.
• Controlled Substance: Not a controlled substance.
• Labeling: Complies with the FDA’s labeling requirements for prescription medications.

FAQ:

1. What is ARIMIROW 1MG/50 TABS used for?
ARIMIROW (Anastrozole) is primarily used to treat breast cancer in postmenopausal women by lowering estrogen levels, which may help slow the growth of hormone receptor-positive breast cancer.

2. How should I take ARIMIROW?
Typically, you should take one 1 mg tablet per day, with or without food, as prescribed by your doctor.

3. Are there any side effects?
Common side effects include hot flashes, joint pain, and headaches. Contact your doctor if you experience severe side effects like chest pain or difficulty breathing.

4. Can I take ARIMIROW with other medications?
Consult your healthcare provider before combining ARIMIROW with other medications, as some drugs may interact with Anastrozole.

5. How should I store ARIMIROW?
Store the tablets at room temperature, away from light and moisture, in a tightly closed container.

Conclusion:

ARIMIROW 1MG/50 TABS (Anastrozole) is a highly effective, prescription-only medication used in the management of breast cancer. Its ability to block estrogen production makes it a key treatment option for postmenopausal women with hormone receptor-positive breast cancer. As with any medication, follow proper safety and storage guidelines to ensure its effectiveness and longevity.